Nicotine stabilization in composite sodium alginate based wafers and films for nicotine replacement therapy
نویسندگان
چکیده
منابع مشابه
Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy.
Smoking cessation is of current topical interest due to the significant negative health and economic impact in many countries. This study aimed to develop buccal films and wafers comprising HPMC and sodium alginate (SA) for potential use in nicotine replacement therapy via the buccal mucosa, as a cheap but effective alternative to currently used nicotine patch and chewing gum. The formulations ...
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There are a large number of smokers who want to quit smoking but have failed in their attempts to do so, with many having been unsuccessful at quitting multiple times over their lifetime. The existing marketed nicotine replacement therapies (NRT) have only marginal effectiveness and none provide a comparable physiological response to that derived from cigarette smoking; that is, rapid absorptio...
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OBJECTIVE To review the literature on nicotine dependence, nicotine pharmacology, health consequences associated with the use of nicotine, and nicotine replacement therapies used to aid smokers who are nicotine dependent. DATA SOURCES A review of articles, book bibliographies, and published studies identified by a search of the MEDLINE database from 1982 to 1996 on nicotine dependence, nicoti...
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This review discusses the known cardiovascular effects of smoking and the effects of nicotine without tobacco smoke and interprets the available data on cardiovascular risk during nicotine replacement therapy (NRT). Nicotine gum and patches are now approved for over the counter sale in the United States. Smokers with cardiovascular disease are advised to seek physician counseling before using n...
متن کاملNicotine replacement therapy in pregnancy.
Cigarette smoking is a major modifiable cause of adverse pregnancy outcomes. Nicotine-replacement therapy (NRT) is recommended in guidelines, but its efficacy and safety during pregnancy is uncertain. This multicentre double-blind trial recruited 1050 pregnant participants who were in their 12–24 weeks’ gestation periods. All of them smoked ≥5 cigarettes per day (median 20). Participants were r...
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ژورنال
عنوان ژورنال: Carbohydrate Polymers
سال: 2017
ISSN: 0144-8617
DOI: 10.1016/j.carbpol.2016.08.053